Krumm, Brian E.: search on Z-Library

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1

Technical, Biological, and Systems Barriers for Molecular Clinical Decision Support

Krumm, Niklas, Shirts, Brian H.

Journal:

Clinics in Laboratory Medicine

Year:

2019

Language:

english

File:

PDF, 242 KB

english, 2019

2

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

O’Roak, Brian J., Vives, Laura, Girirajan, Santhosh, Karakoc, Emre, Krumm, Niklas, Coe, Bradley P., Levy, Roie, Ko, Arthur, Lee, Choli, Smith, Joshua D., Turner, Emily H., Stanaway, Ian B., Vernot, Be

Journal:

Year:

2012

Language:

english

File:

PDF, 458 KB

english, 2012

3

A Unique Bivalent Binding and Inhibition Mechanism by the Yatapoxvirus Interleukin 18 Binding Protein

Krumm, Brian, Meng, Xiangzhi, Wang, Zhixin, Xiang, Yan, Deng, Junpeng, Buller, R. Mark L.

Journal:

Year:

2012

Language:

english

File:

PDF, 4.53 MB

english, 2012

4

A de novo convergence of autism genetics and molecular neuroscience

Krumm, Niklas, O’Roak, Brian J., Shendure, Jay, Eichler, Evan E.

Journal:

Trends in Neurosciences

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

5

Gambogic Acid, a Natural Product Inhibitor of Hsp90

Davenport, Jason, Manjarrez, Jacob R., Peterson, Laura, Krumm, Brian, Blagg, Brian S. J., Matts, Robert L.

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

6

Identification of small molecule inhibitors of Interleukin-18

Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

7

Nanobody-enabled monitoring of kappa opioid receptor states

Che, Tao, English, Justin, Krumm, Brian E., Kim, Kuglae, Pardon, Els, Olsen, Reid H. J., Wang, Sheng, Zhang, Shicheng, Diberto, Jeffrey F., Sciaky, Noah, Carroll, F. Ivy, Steyaert, Jan, Wacker, Daniel

Journal:

Nature Communications

Year:

2020

File:

PDF, 1.95 MB

2020

8

Rare-Variant Extensions of the Transmission Disequilibrium Test: Application to Autism Exome Sequence Data

He, Zongxiao, O’Roak, Brian J., Smith, Joshua D., Wang, Gao, Hooker, Stanley, Santos-Cortez, Regie Lyn P., Li, Biao, Kan, Mengyuan, Krumm, Nik, Nickerson, Deborah A., Shendure, Jay, Eichler, Evan E.,

Journal:

The American Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 649 KB

english, 2014

9

Activation mechanisms for a universal signalling protein

Krumm, Brian, Roth, Bryan L.

Journal:

Year:

2018

Language:

english

File:

PDF, 294 KB

english, 2018

10

The R1441C mutation alters the folding properties of the ROC domain of LRRK2

Yongchao Li, Laura Dunn, Elisa Greggio, Brian Krumm, Graham S. Jackson, Mark R. Cookson, Patrick A. Lewis, Junpeng Deng

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

11

Structural biology of the IL-1 superfamily: Key cytokines in the regulation of immune and inflammatory responses

Krumm, Brian, Xiang, Yan, Deng, Junpeng

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 851 KB

english, 2014

12

The contribution of de novo coding mutations to autism spectrum disorder

Iossifov, Ivan, O’Roak, Brian J., Sanders, Stephan J., Ronemus, Michael, Krumm, Niklas, Levy, Dan, Stessman, Holly A., Witherspoon, Kali T., Vives, Laura, Patterson, Karynne E., Smith, Joshua D., Paep

Journal:

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

13

Structures of Substrate- and Inhibitor-Bound Adenosine Deaminase from a Human Malaria Parasite Show a Dramatic Conformational Change and Shed Light on Drug Selectivity

Eric T. Larson, Wei Deng, Brian E. Krumm, Alberto Napuli, Natascha Mueller, Wesley C. Van Voorhis, Frederick S. Buckner, Erkang Fan, Angela Lauricella, George DeTitta, Joseph Luft, Frank Zucker, Wim G

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 2.73 MB

english, 2008

14

Structure and dynamics of a constitutively active neurotensin receptor

Krumm, Brian E., Lee, Sangbae, Bhattacharya, Supriyo, Botos, Istvan, White, Courtney F., Du, Haijuan, Vaidehi, Nagarajan, Grisshammer, Reinhard

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

15

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

Olsen, Reid H. J., DiBerto, Jeffrey F., English, Justin G., Glaudin, Alexis M., Krumm, Brian E., Slocum, Samuel T., Che, Tao, Gavin, Ariana C., McCorvy, John D., Roth, Bryan L., Strachan, Ryan T.

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 4.39 MB

2020

16

IGF binding protein-3 mediates stress-induced apoptosis in non-transformed mammary epithelial cells

Leibowitz, Brian J., Agostini-Dreyer, Allyson, Jetzt, Amanda E., Krumm, Christopher S., Cohick, Wendie S.

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 440 KB

english, 2013

17

Structural prerequisites for G-protein activation by the neurotensin receptor

Krumm, Brian E., White, Jim F., Shah, Priyanka, Grisshammer, Reinhard

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

18

Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERα

Krumm, Elizabeth A, Patel, Vipa J, Tillery, Taylor S, Yasrebi, Ali, Shen, Jianliang, Guo, Grace L, Marco, Stephanie M, Buckley, Brian T, Roepke, Troy A

Journal:

Toxicological Sciences

Year:

2017

Language:

english

File:

PDF, 851 KB

english, 2017

19

Crystallization of interleukin-18 for structure-based inhibitor design

Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

20

Crystal Structure of the Extracellular Protein Secretion NTPase EpsE of Vibrio cholerae

Mark A. Robien, Brian E. Krumm, Maria Sandkvist, Wim G.J. Hol

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 5.65 MB

english, 2003

21

A self-activating orphan receptor

Krumm, Brian, Roth, Bryan L.

Journal:

Year:

2020

Language:

english

File:

PDF, 233 KB

english, 2020

22

2017 Transactional Clinic Conference -- June 1-2, 2017 Philadelphia. Results of a Survey of Conference Participants on Skills, Competencies, Learning Outcomes and Assessments (And Other Transactional Clinic Demographics)

Wagner, Barbara, O'Connor, Gerard, Vachon, Christyne J., Krumm, Brian Kingsley

Journal:

SSRN Electronic Journal

Year:

2017

Language:

english

File:

PDF, 537 KB

english, 2017

23

How Many Attempts Are Needed to Achieve General Surgery Board Certification?

Abbott, Kenneth L., Kendrick, Daniel E., Chen, Xilin, Krumm, Andrew E., Jones, Andrew T., George, Brian C.

Journal:

Journal of Surgical Education

Year:

2020

File:

PDF, 167 KB

2020

24

Transmission Disequilibrium of Small CNVs in Simplex Autism

Krumm, Niklas, O’Roak, Brian J., Karakoc, Emre, Mohajeri, Kiana, Nelson, Ben, Vives, Laura, Jacquemont, Sebastien, Munson, Jeff, Bernier, Raphe, Eichler, Evan E.

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 873 KB

english, 2013

25

Peptide ligand recognition by G protein-coupled receptors

Krumm, Brian E., Grisshammer, Reinhard

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 367 KB

english, 2015

26

Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins

Meng, Xiangzhi, Krumm, Brian, Li, Yongchao, Deng, Junpeng, Xiang, Yan

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

27

A Structural Understanding of Class B GPCR Selectivity and Activation Revealed

Krumm, Brian, Roth, Bryan L.

Journal:

Year:

2020

File:

PDF, 642 KB

2020

28

Structural biology and structure-based inhibitor design of cholera toxin and heat-labile enterotoxin

Erkang Fan, Claire J. O’Neal, Daniel D. Mitchell, Mark A. Robien, Zhongsheng Zhang, Jason C. Pickens, Xiao-Jian Tan, Konstantin Korotkov, Claudia Roach, Brian Krumm, Christophe L.M.J. Verlinde, Ethan

Journal:

International Journal of Medical Microbiology

Year:

2004

Language:

english

File:

PDF, 448 KB

english, 2004

29

Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae

Konstantin V. Korotkov, Brian Krumm, Michael Bagdasarian, Wim G.J. Hol

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

30

[ACM Press the 13th international conference - Beijing, China (2011.09.17-2011.09.21)] Proceedings of the 13th international conference on Ubiquitous computing - UbiComp '11 - PreHeat

Scott, James, Bernheim Brush, A.J., Krumm, John, Meyers, Brian, Hazas, Michael, Hodges, Stephen, Villar, Nicolas

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

31

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Che, Tao, Majumdar, Susruta, Zaidi, Saheem A., Ondachi, Pauline, McCorvy, John D., Wang, Sheng, Mosier, Philip D., Uprety, Rajendra, Vardy, Eyal, Krumm, Brian E., Han, Gye Won, Lee, Ming-Yue, Pardon,

Journal:

Year:

2018

Language:

english

File:

PDF, 7.26 MB

english, 2018

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